The immunosuppressive microenvironment and immunotherapy in human glioblastoma

Glioblastoma multiforme (GBM) is the most malignant intracranial tumor in adults, characterized by extensive infiltrative growth, high vascularization, and resistance to multiple therapeutic approaches. Among the many factors affecting the therapeutic effect, the immunosuppressive GBM microenvironme...

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Bibliographic Details
Main Authors: Xuehua Zhang, Leilei Zhao, He Zhang, Yurui Zhang, Huanyu Ju, Xiaoyu Wang, Huan Ren, Xiao Zhu, Yucui Dong
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1003651/full