TNF-α protein synthesis inhibitor restores neuronal function and reverses cognitive deficits induced by chronic neuroinflammation
<p>Abstract</p> <p>Background</p> <p>Chronic neuroinflammation is a hallmark of several neurological disorders associated with cognitive loss. Activated microglia and secreted factors such as tumor necrosis factor (TNF)-α are key mediators of neuroinflammation and may c...
Main Authors: | Belarbi Karim, Jopson Timothy, Tweedie David, Arellano Carla, Luo Weiming, Greig Nigel H, Rosi Susanna |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2012-01-01
|
Series: | Journal of Neuroinflammation |
Subjects: | |
Online Access: | http://www.jneuroinflammation.com/content/9/1/23 |
Similar Items
-
Distinct epigenetic and gene expression changes in rat hippocampal neurons after Morris water maze training
by: Sylvia D. eCarter, et al.
Published: (2015-06-01) -
Clinical performance of immediately placed and restored progressive-type implants in the esthetic zone: a prospective observational study
by: G. Trimpou, et al.
Published: (2022-11-01) -
Therapeutic targets of the TNF superfamily /
by: Grewal, Iqbal S.
Published: (2009) -
Comparative Analysis of TNF-alpha, TNF-R1, and TNF-R2 in Patients with Low-impact Fractures Due to Osteoporosis
by: Abel Oliveira Marques Teixeira, et al.
Published: (2023-07-01) -
Effect of repeated seizures on spatial exploration and immediate early gene expression in the hippocampus and dentate gyrus
by: Alena Kalinina, et al.
Published: (2022-06-01)