Helicobacter pylori infection induces gastric precancerous lesions and persistent expression of Angpt2, Vegf-A and Tnf-A in a mouse model

Helicobacter pylori infection induces gastric precancerous lesions and persistent expression of Angpt2, Vegf-A and Tnf-A in a mouse model

IntroductionHelicobacter pylori colonizes the gastric mucosa and induces chronic inflammation. MethodsUsing a mouse model of H. pylori-induced gastritis, we evaluated the mRNA and protein expression levels of proinflammatory and proangiogenic factors, as well as the histopathological changes in gast...

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Bibliographic Details
Main Authors: Wendy Malespín-Bendaña, Warner Alpízar-Alpízar, Lucía Figueroa-Protti, Ledis Reyes, Silvia Molina-Castro, Clas Une, Vanessa Ramírez-Mayorga
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Oncology
Subjects:
Helicobacter pylori
angiogenesis
ANGPT1
ANGPT2
VEGFA
mouse model
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1072802/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2023.1072802/full

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