Clinical Pharmacogenetics of Cytochrome P450-Associated Drugs in Children

Clinical Pharmacogenetics of Cytochrome P450-Associated Drugs in Children

Cytochrome P450 (CYP) enzymes are commonly involved in drug metabolism, and genetic variation in the genes encoding CYPs are associated with variable drug response. While genotype-guided therapy has been clinically implemented in adults, these associations are less well established for pediatric pat...

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Bibliographic Details
Main Authors: Ida Aka, Christiana J. Bernal, Robert Carroll, Angela Maxwell-Horn, Kazeem A. Oshikoya, Sara L. Van Driest
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:Journal of Personalized Medicine
Subjects:
pediatrics
pharmacogenomics
electronic health records
drug–gene interactions
cytochrome P450
Online Access:https://www.mdpi.com/2075-4426/7/4/14

Internet

https://www.mdpi.com/2075-4426/7/4/14

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