Late-onset neutropenia following rituximab results from a hematopoietic lineage competition due to an excessive BAFF-induced B-cell recovery

Rituximab is used in the treatment of lymphoma and autoimmune diseases, for which late-onset neutropenia (LON) were reported. LON-related mechanisms remain unclear. To obtain insights into the mechanisms, we assessed serum, peripheral blood and bone marrow (BM) samples of a patient with LON. Factors...

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Bibliographic Details
Main Authors: B. Terrier, M. Ittah, L. Tourneur, F. Louache, V. Soumelis, F. Lavie, N. Casadevall, S. Candon, A. Hummel, X. Mariette, A. Buzyn
Format: Article
Language:English
Published: Ferrata Storti Foundation 2007-02-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/4356