Loss of PLZF expression in prostate cancer by immunohistochemistry correlates with tumor aggressiveness and metastasis.

Loss of PLZF expression in prostate cancer by immunohistochemistry correlates with tumor aggressiveness and metastasis.

PLZF is a transcription repressor, which plays a critical role in development, spermatogenesis and oncogenesis. Down-regulation of PLZF has been found in various tumor cell lines. There has been virtually no tissue study on the expression of PLZF in prostate cancer (PCa). PCa is a heterogeneous dise...

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Bibliographic Details
Main Authors: Guang-Qian Xiao, Pamela Unger, Qi Yang, Yayoi Kinoshita, Kyra Singh, Loralee McMahon, Kent Nastiuk, Kai Sha, John Krolewski, David Burstein
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4373907?pdf=render

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http://europepmc.org/articles/PMC4373907?pdf=render

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