5-Lipoxygenase DNA Methylation and mRNA Content in the Brain and Heart of Young and Old Mice
The expression of 5-lipoxygenase (5-LOX) is affected by aging and regulated by epigenetic mechanisms including DNA methylation. We used methylation-sensitive restriction endonucleases (AciI, BstUI, HpaII, and HinP1I) to assess 5-LOX DNA methylation in brain and heart tissue samples from young (2 mo...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Hindawi Limited
2009-01-01
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| Series: | Neural Plasticity |
| Online Access: | http://dx.doi.org/10.1155/2009/209596 |