Development and technical validation of an ultrasound nebulizer to deliver intraperitoneal pressurized aerosols in a rat colon cancer peritoneal metastases model

Development and technical validation of an ultrasound nebulizer to deliver intraperitoneal pressurized aerosols in a rat colon cancer peritoneal metastases model

Abstract Background/aim To develop and validate a nebulizer device for anti-cancer research on pressurized intraperitoneal aerosol supply in a preclinical peritoneal metastases (PM) rat model. Material and methods For aerosol generation, an ultrasonic nebulizer (USN) was modified. Aerosol analyses w...

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Bibliographic Details
Main Authors: Jonathan R. Buggisch, Daniel Göhler, Julien Sobilo, Stéphanie Lerondel, Günther A. Rezniczek, Michael Stintz, Andreas Rudolph, Nicolas Tabchouri, Sébastien Roger, Mehdi Ouaissi, Urs Giger-Pabst
Format: Article
Language:English
Published: BMC 2022-05-01
Series:BMC Cancer
Subjects:
Peritoneal metastasis
Human colorectal cancer cells
Orthotopic rat model
Ultrasonic nebulizer
Intraperitoneal pressurized aerosol
Online Access:https://doi.org/10.1186/s12885-022-09668-0

Internet

https://doi.org/10.1186/s12885-022-09668-0

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