Antigen-encapsulating host extracellular vesicles derived from Salmonella-infected cells stimulate pathogen-specific Th1-type responses in vivo.

Antigen-encapsulating host extracellular vesicles derived from Salmonella-infected cells stimulate pathogen-specific Th1-type responses in vivo.

Salmonella Typhimurium is a causative agent of nontyphoidal salmonellosis, for which there is a lack of a clinically approved vaccine in humans. As an intracellular pathogen, Salmonella impacts many cellular pathways. However, the intercellular communication mechanism facilitated by host-derived sma...

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Bibliographic Details
Main Authors: Winnie W Hui, Lisa E Emerson, Beata Clapp, Austin E Sheppe, Jatin Sharma, Johanna Del Castillo, Mark Ou, Gustavo H B Maegawa, Carol Hoffman, Joseph Larkin Iii, David W Pascual, Mariola J Ferraro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-05-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009465

Internet

https://doi.org/10.1371/journal.ppat.1009465

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