Antigen-encapsulating host extracellular vesicles derived from Salmonella-infected cells stimulate pathogen-specific Th1-type responses in vivo.
Salmonella Typhimurium is a causative agent of nontyphoidal salmonellosis, for which there is a lack of a clinically approved vaccine in humans. As an intracellular pathogen, Salmonella impacts many cellular pathways. However, the intercellular communication mechanism facilitated by host-derived sma...
Main Authors: | Winnie W Hui, Lisa E Emerson, Beata Clapp, Austin E Sheppe, Jatin Sharma, Johanna Del Castillo, Mark Ou, Gustavo H B Maegawa, Carol Hoffman, Joseph Larkin Iii, David W Pascual, Mariola J Ferraro |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2021-05-01
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Series: | PLoS Pathogens |
Online Access: | https://doi.org/10.1371/journal.ppat.1009465 |
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