MicroRNAs: exploring a new dimension in the pathogenesis of kidney cancer

<p>Abstract</p> <p>Renal cell carcinoma (RCC) is the most common neoplasm of the adult kidney. The role of the von-Hippel-Lindeau (VHL) tumour suppressor gene is well established in RCC with a loss of VHL protein leading to accumulated hypoxia-induced factor (HIF) and the subsequen...

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Bibliographic Details
Main Authors: Yousef George M, White Nicole MA
Format: Article
Language:English
Published: BMC 2010-10-01
Series:BMC Medicine
Online Access:http://www.biomedcentral.com/1741-7015/8/65