Mounting, structure and autocleavage of a type VI secretion-associated Rhs polymorphic toxin

Rearrangement hot spots (Rhs) proteins are bacterial polymorphic toxin systems. Here, the authors show that Rhs1 forms a complex with the Type VI secretion system (T6SS) spike protein VgrG and the EagR chaperone. They also present the cryo-EM structure of the Rhs1-EagR complex and propose a model fo...

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Bibliographic Details
Main Authors: Dukas Jurėnas, Leonardo Talachia Rosa, Martial Rey, Julia Chamot-Rooke, Rémi Fronzes, Eric Cascales
Format: Article
Language:English
Published: Nature Portfolio 2021-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-27388-0