Large-scale 3D chromatin reconstruction from chromosomal contacts

Abstract Background Recent advances in genome analysis have established that chromatin has preferred 3D conformations, which bring distant loci into contact. Identifying these contacts is important for us to understand possible interactions between these loci. This has motivated the creation of the...

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Bibliographic Details
Main Authors: Yanlin Zhang, Weiwei Liu, Yu Lin, Yen Kaow Ng, Shuaicheng Li
Format: Article
Language:English
Published: BMC 2019-04-01
Series:BMC Genomics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12864-019-5470-2