Improved production of the non-native cofactor F420 in Escherichia coli

Abstract The deazaflavin cofactor F420 is a low-potential, two-electron redox cofactor produced by some Archaea and Eubacteria that is involved in methanogenesis and methanotrophy, antibiotic biosynthesis, and xenobiotic metabolism. However, it is not produced by bacterial strains commonly used for...

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Bibliographic Details
Main Authors: Mihir V. Shah, Hadi Nazem-Bokaee, James Antoney, Suk Woo Kang, Colin J. Jackson, Colin Scott
Format: Article
Language:English
Published: Nature Portfolio 2021-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-01224-3