HCV Drug Resistance Challenges in Japan: The Role of Pre-Existing Variants and Emerging Resistant Strains in Direct Acting Antiviral Therapy

Sustained virological response (SVR) rates have increased dramatically following the approval of direct acting antiviral (DAA) therapies. While individual DAAs have a low barrier to resistance, most patients can be successfully treated using DAA combination therapy. However, DAAs are vulnerable to d...

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Bibliographic Details
Main Authors: Kazuaki Chayama, C. Nelson Hayes
Format: Article
Language:English
Published: MDPI AG 2015-10-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/7/10/2876