Insights into the Antioxidant Mechanism of Newly Synthesized Benzoxazinic Nitrones: In Vitro and In Silico Studies with DPPH Model Radical

Insights into the Antioxidant Mechanism of Newly Synthesized Benzoxazinic Nitrones: In Vitro and In Silico Studies with DPPH Model Radical

Synthetic nitrone spin-traps are being explored as therapeutic agents for the treatment of a wide range of oxidative stress-related pathologies, including but not limited to stroke, cancer, cardiovascular, and neurodegenerative diseases. In this context, increasing efforts are currently being made t...

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Bibliographic Details
Main Authors: Stefania Marano, Cristina Minnelli, Lorenzo Ripani, Massimo Marcaccio, Emiliano Laudadio, Giovanna Mobbili, Adolfo Amici, Tatiana Armeni, Pierluigi Stipa
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Antioxidants
Subjects:
free radicals
nitrone
DPPH
antioxidant
electron paramagnetic resonance (EPR)
density functional theory (DTF)
Online Access:https://www.mdpi.com/2076-3921/10/8/1224

Internet

https://www.mdpi.com/2076-3921/10/8/1224

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