Differential, Stage Dependent Detection of Peptidylarginine Deiminases and Protein Deimination in Lewy Body Diseases—Findings from a Pilot Study

Differential, Stage Dependent Detection of Peptidylarginine Deiminases and Protein Deimination in Lewy Body Diseases—Findings from a Pilot Study

Over 10 million people worldwide live with Parkinson’s disease (PD) and 4% of affected people are diagnosed before the age of 50. Research on early PD-related pathways is therefore of considerable importance. Peptidylarginine deiminases (PADs) are a family of calcium-activated enzymes that, through...

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Bibliographic Details
Main Authors: Audrey Mercer, Zane Jaunmuktane, Mariya Hristova, Sigrun Lange
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
peptidylarginine deiminase
deimination/citrullination
post-translational modification
histone H3
neurodegeneration
Parkinson’s disease
Online Access:https://www.mdpi.com/1422-0067/23/21/13117

Internet

https://www.mdpi.com/1422-0067/23/21/13117

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