Distinct clinical phenotypes in paediatric cancer patients with sepsis are associated with different outcomes—an international multicentre retrospective studyResearch in context

Distinct clinical phenotypes in paediatric cancer patients with sepsis are associated with different outcomes—an international multicentre retrospective studyResearch in context

Summary: Background: Identifying phenotypes in sepsis patients may enable precision medicine approaches. However, the generalisability of these phenotypes to specific patient populations is unclear. Given that paediatric cancer patients with sepsis have different host response and pathogen profiles...

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Main Authors: Roelie M. Wösten-van Asperen, Hannah M. la Roi-Teeuw, Rombout BE. van Amstel, Lieuwe DJ. Bos, Wim JE. Tissing, Iolanda Jordan, Christian Dohna-Schwake, Gabriella Bottari, John Pappachan, Roman Crazzolara, Rosanna I. Comoretto, Agniezka Mizia-Malarz, Andrea Moscatelli, María Sánchez-Martín, Jef Willems, Colin M. Rogerson, Tellen D. Bennett, Yuan Luo, Mihir R. Atreya, E.Vincent S. Faustino, Alon Geva, Scott L. Weiss, Luregn J. Schlapbach, L Nelson Sanchez-Pinto, Marina Caballero, Adriana Margarit, Roi Campos, Paula Möller, Carmela Serpe, Angela Amigoni, Maria Damps, Alessia Montaguti, Giacomo Tardini, Juliane Bubeck-Wardenburg, Reid Farris Farris, Mark Hall, Grace Chong, Sareen Shah, Robinder Khemani, Emily Stroup
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:EClinicalMedicine
Subjects:
Paediatric intensive care
Oncology
Sepsis
Phenotype
Latent class analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2589537023004297

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http://www.sciencedirect.com/science/article/pii/S2589537023004297

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