Structural Basis of <i>Clostridium perfringens</i> Enterotoxin Activation and Oligomerization by Trypsin
Clostridium perfringens enterotoxin (CpE) is a β-pore forming toxin that disrupts gastrointestinal homeostasis in mammals by binding membrane protein receptors called claudins. Although structures of CpE fragments bound to claudins have been determined, the mechanisms that trigger CpE activation and...
| Hoofdauteurs: | , , |
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| Formaat: | Artikel |
| Taal: | English |
| Gepubliceerd in: |
MDPI AG
2023-10-01
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| Reeks: | Toxins |
| Onderwerpen: | |
| Online toegang: | https://www.mdpi.com/2072-6651/15/11/637 |