Cold Press Pomegranate Seed Oil Attenuates Dietary-Obesity Induced Hepatic Steatosis and Fibrosis through Antioxidant and Mitochondrial Pathways in Obese Mice

Cold Press Pomegranate Seed Oil Attenuates Dietary-Obesity Induced Hepatic Steatosis and Fibrosis through Antioxidant and Mitochondrial Pathways in Obese Mice

Aim: Obesity is associated with metabolic syndrome, hypertension, dyslipidemia, nonalcoholic fatty liver disease (NAFLD), and type 2 diabetes. In this study, we investigated whether the dietary supplementation of pomegranate seed oil (PSO) exerted a protective effect on liver lipid uptake, fibrosis,...

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Bibliographic Details
Main Authors: Marco Raffaele, Maria Licari, Sherif Amin, Ragin Alex, Hsin-hsueh Shen, Shailendra P. Singh, Luca Vanella, Rita Rezzani, Francesca Bonomini, Stephen J. Peterson, David E. Stec, Nader G. Abraham
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:International Journal of Molecular Sciences
Subjects:
obesity
ROS
oxygen consumption
heme-oxygenase (HO-1)
PGC-1α
insulin resistance
Online Access:https://www.mdpi.com/1422-0067/21/15/5469

Internet

https://www.mdpi.com/1422-0067/21/15/5469

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