Using structural information to change the phosphotransfer specificity of a two-component chemotaxis signalling complex.
Two-component signal transduction pathways comprising histidine protein kinases (HPKs) and their response regulators (RRs) are widely used to control bacterial responses to environmental challenges. Some bacteria have over 150 different two-component pathways, and the specificity of the phosphotrans...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2010-02-01
|
| Series: | PLoS Biology |
| Online Access: | http://europepmc.org/articles/PMC2817712?pdf=render |