Oxidative Stress Induced by Reactive Oxygen Species (ROS) and NADPH Oxidase 4 (NOX4) in the Pathogenesis of the Fibrotic Process in Systemic Sclerosis: A Promising Therapeutic Target

Oxidative Stress Induced by Reactive Oxygen Species (ROS) and NADPH Oxidase 4 (NOX4) in the Pathogenesis of the Fibrotic Process in Systemic Sclerosis: A Promising Therapeutic Target

Numerous clinical and research investigations conducted during the last two decades have implicated excessive oxidative stress caused by high levels of reactive oxygen species (ROS) in the development of the severe and frequently progressive fibrotic process in Systemic Sclerosis (SSc). The role of...

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Bibliographic Details
Main Authors: Sonsoles Piera-Velazquez, Sergio A. Jimenez
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Journal of Clinical Medicine
Subjects:
fibrosis
systemic sclerosis
oxidative stress
reactive oxygen species
NADPH
NOX4
Online Access:https://www.mdpi.com/2077-0383/10/20/4791

Internet

https://www.mdpi.com/2077-0383/10/20/4791

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