Specific tritium labeling of gangliosides at the 3-position of sphingosines.

GM1 and GD1a gangliosides, treated with 2,3-dichloro-5,6-dicyano benzoquinone (DDQ) in the presence of Triton X-100 and in a toluene medium were specifically oxidized at the 3-position of sphingosine. The maximum reaction yield (65%) was obtained after 40 hours at 37 degrees C with the following mol...

Full description

Bibliographic Details
Main Authors: R Ghidoni, S Sonnino, M Masserini, P Orlando, G Tettamanti
Format: Article
Language:English
Published: Elsevier 1981-11-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520373223