Real-Time Predictions of Reservoir Size and Rebound Time during Antiretroviral Therapy Interruption Trials for HIV.

Monitoring the efficacy of novel reservoir-reducing treatments for HIV is challenging. The limited ability to sample and quantify latent infection means that supervised antiretroviral therapy (ART) interruption studies are generally required. Here we introduce a set of mathematical and statistical m...

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Detalles Bibliográficos
Main Authors: Alison L Hill, Daniel I S Rosenbloom, Edward Goldstein, Emily Hanhauser, Daniel R Kuritzkes, Robert F Siliciano, Timothy J Henrich
Formato: Artigo
Idioma:English
Publicado: Public Library of Science (PLoS) 2016-04-01
Series:PLoS Pathogens
Acceso en liña:http://europepmc.org/articles/PMC4847932?pdf=render