Combining bacteriophage and vancomycin is efficacious against MRSA biofilm-like aggregates formed in synovial fluid

Combining bacteriophage and vancomycin is efficacious against MRSA biofilm-like aggregates formed in synovial fluid

BackgroundBiofilm formation is a major clinical challenge contributing to treatment failure of periprosthetic joint infection (PJI). Lytic bacteriophages (phages) can target biofilm associated bacteria at localized sites of infection. The aim of this study is to investigate whether combination thera...

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Bibliographic Details
Main Authors: Mariam Taha, Tia Arnaud, Tasia J. Lightly, Danielle Peters, Liyuan Wang, Wangxue Chen, Bradley W. M. Cook, Steven S. Theriault, Hesham Abdelbary
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Medicine
Subjects:
biofilm
synovial fluid
aggregates
Staphylococcus aureus
phage
vancomycin
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2023.1134912/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2023.1134912/full

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