Chlorogenic acid against palmitic acid in endoplasmic reticulum stress-mediated apoptosis resulting in protective effect of primary rat hepatocytes

Abstract Background We demonstrated growing evidence supports a protective role of chlorogenic acid of rat hepatocytes elicited by two compounds, i.e. thapsigargin and palmitic acid. Nevertheless, little is known about the mechanisms of palmitic acid induced endoplasmic reticulum (ER) stress and cel...

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Bibliographic Details
Main Authors: Yong Zhang, Liangsheng Miao, Huijuan Zhang, Gang Wu, Zhenni Zhang, Jianrui Lv
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Lipids in Health and Disease
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12944-018-0916-0