Liver sinusoidal cells eliminate blood-borne phage K1F

Liver sinusoidal cells eliminate blood-borne phage K1F

ABSTRACTPhage treatment has regained attention due to an increase in multiresistant bacteria. For phage therapy to be successful, phages must reach their target bacteria in sufficiently high numbers. Blood-borne phages are believed to be captured by macrophages in the liver and spleen. Since liver s...

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Bibliographic Details
Main Authors: Javier Sánchez Romano, Jaione Simón-Santamaría, Peter McCourt, Bård Smedsrød, Kim Erlend Mortensen, Antonia P. Sagona, Karen Kristine Sørensen, Anett Kristin Larsen
Format: Article
Language:English
Published: American Society for Microbiology 2024-03-01
Series:mSphere
Subjects:
bacteriophage
blood clearance
Kupffer cells
liver sinusoidal endothelial cells
organ distribution
scavenger cells
Online Access:https://journals.asm.org/doi/10.1128/msphere.00702-23

Internet

https://journals.asm.org/doi/10.1128/msphere.00702-23

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