Origin of the Time Lag Phenomenon and the Global Signal in Resting-State fMRI

The global mean signal of resting-state fMRI (rs-fMRI) shows a characteristic spatiotemporal pattern that is closely related to the pattern of vascular perfusion. Although being increasingly adopted in the mapping of the flow of neural activity, the mechanism that gives rise to the BOLD signal time...

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Bibliographic Details
Main Authors: Shiori Amemiya, Hidemasa Takao, Osamu Abe
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2020.596084/full