Anti-leishmanial activity of Eleutherine plicata Herb. and predictions of isoeleutherin and its analogues

Anti-leishmanial activity of Eleutherine plicata Herb. and predictions of isoeleutherin and its analogues

Introduction: Leishmaniasis is caused by protozoa of the genus Leishmania, classified as tegumentary and visceral. The disease treatment is still a serious problem, due to the toxic effects of available drugs, the costly treatment and reports of parasitic resistance, making the search for therapeuti...

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Main Authors: Kelly Cristina Oliveira de Albuquerque, Andreza do Socorro Silva da Veiga, Fernando Tobias Silveira, Marliane Batista Campos, Ana Paula Lima da Costa, Ananda Karolyne Martins Brito, Paulo Ricardo de Souza Melo, Sandro Percario, Fábio Alberto de Molfetta, Maria Fâni Dolabela
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Chemistry
Subjects:
isoeleutherin
trypanothione reductase
antiamastigote activity
naftoquinones
medical plant
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2024.1341172/full

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https://www.frontiersin.org/articles/10.3389/fchem.2024.1341172/full

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