Seizure enhances SUMOylation and zinc-finger transcriptional repression in neuronal nuclei

Summary: A single episode of pilocarpine-induced status epilepticus can trigger the development of spontaneous recurrent seizures in a rodent model for epilepsy. The initial seizure-induced events in neuronal nuclei that lead to long-term changes in gene expression and cellular responses likely cont...

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Bibliographic Details
Main Authors: Hui Rong Soon, Jessica Ruth Gaunt, Vibhavari Aysha Bansal, Clara Lenherr, Siu Kwan Sze, Toh Hean Ch’ng
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223017844