Efficiency of antioxidant Avenanthramide-C on high-dose methotrexate-induced ototoxicity in mice.
Methotrexate (MTX) has been used in treating various types of cancers but can also cause damage to normal organs and cell types. Folinic acid (FA) is a well-known MTX antidote that protects against toxicity caused by the drug and has been used for decades. Since hearing loss caused by MTX treatment...
Main Authors: | Alphonse Umugire, Youngmi Choi, Sungsu Lee, Hyong-Ho Cho |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2022-01-01
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Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0266108 |
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