Mitochondrial Dysfunction and Impaired Antioxidant Responses in Retinal Pigment Epithelial Cells Derived from a Patient with <i>RCBTB1</i>-Associated Retinopathy

Mitochondrial Dysfunction and Impaired Antioxidant Responses in Retinal Pigment Epithelial Cells Derived from a Patient with <i>RCBTB1</i>-Associated Retinopathy

Mutations in the <i>RCBTB1</i> gene cause inherited retinal disease; however, the pathogenic mechanisms associated with RCBTB1 deficiency remain poorly understood. Here, we investigated the effect of RCBTB1 deficiency on mitochondria and oxidative stress responses in induced pluripotent...

Full description

Bibliographic Details
Main Authors: Zhiqin Huang, Dan Zhang, Shang-Chih Chen, Di Huang, David Mackey, Fred K. Chen, Samuel McLenachan
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Cells
Subjects:
RCBTB1
inherited retinal disease
retinal pigment epithelium
oxidative stress
mitochondria
Online Access:https://www.mdpi.com/2073-4409/12/10/1358

Internet

https://www.mdpi.com/2073-4409/12/10/1358

Similar Items