How do antimalarial drugs reach their intracellular targets?

Drugs represent the primary treatment available for human malaria, as caused by Plasmodium spp. Currently approved drugs and antimalarial drug leads generally work against parasite enzymes or activities within infected erythrocytes. To reach their specific targets, these chemicals must cross at le...

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Bibliographic Details
Main Authors: Katherine eBasore, Yang eCheng, Ambuj K. Kushwaha, Son T. Nguyen, Sanjay A. Desai
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-05-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00091/full