Joint analysis of scATAC-seq datasets using epiConv

Abstract Background Technical improvement in ATAC-seq makes it possible for high throughput profiling the chromatin states of single cells. However, data from multiple sources frequently show strong technical variations, which is referred to as batch effects. In order to perform joint analysis acros...

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Bibliographic Details
Main Authors: Li Lin, Liye Zhang
Format: Article
Language:English
Published: BMC 2022-07-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-022-04858-w