Prohibitin 1 interacts with p53 in the regulation of mitochondrial dynamics and chemoresistance in gynecologic cancers

Prohibitin 1 interacts with p53 in the regulation of mitochondrial dynamics and chemoresistance in gynecologic cancers

Abstract Background Mitochondrial dynamics (e.g. fission/fusion) play an important role in controlling chemoresistance in representative gynecologic malignancies, ovarian and cervical cancer. Processing the long form of Optic atrophy (L-Opa)1 is a distinctive character of mitochondrial fragmentation...

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Bibliographic Details
Main Authors: Bao Kong, Chae Young Han, Se Ik Kim, David A. Patten, Youngjin Han, Euridice Carmona, Dar-Bin Shieh, Annie C. Cheung, Anne-Marie Mes-Masson, Mary-Ellen Harper, Yong Sang Song, Benjamin K. Tsang
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Journal of Ovarian Research
Subjects:
Phb1
p53
Bak
CDDP
Mitochondrial fragmentation
Chemoresistance
Online Access:https://doi.org/10.1186/s13048-022-00999-x

Internet

https://doi.org/10.1186/s13048-022-00999-x

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