A Progress Report and Roadmap for Microphysiological Systems and Organ-On-A-Chip Technologies to Be More Predictive Models in Human (Knee) Osteoarthritis

A Progress Report and Roadmap for Microphysiological Systems and Organ-On-A-Chip Technologies to Be More Predictive Models in Human (Knee) Osteoarthritis

Osteoarthritis (OA), a chronic debilitating joint disease affecting hundreds of million people globally, is associated with significant pain and socioeconomic costs. Current treatment modalities are palliative and unable to stop the progressive degeneration of articular cartilage in OA. Scientific a...

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Bibliographic Details
Main Authors: Mario Rothbauer, Eva I. Reihs, Anita Fischer, Reinhard Windhager, Florien Jenner, Stefan Toegel
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
osteoarthritis
organs-on-a-chip
microphysiological system (MPS)
roadmap
disease modeling
alternative methods to animal testing
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.886360/full

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https://www.frontiersin.org/articles/10.3389/fbioe.2022.886360/full

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