1-(4-Nitrophenyl)-1<i>H</i>-1,2,3-Triazole-4-carbaldehyde: Scalable Synthesis and Its Use in the Preparation of 1-Alkyl-4-Formyl-1,2,3-triazoles

1-(4-Nitrophenyl)-1<i>H</i>-1,2,3-Triazole-4-carbaldehyde: Scalable Synthesis and Its Use in the Preparation of 1-Alkyl-4-Formyl-1,2,3-triazoles

1,2,3-Triazole-4-carbaldehydes are useful synthetic intermediates which may play an important role in the discovery of novel applications of the 1,2,3-triazole moiety. In this work, a one-step multigram scale synthesis of 4-formyl-1-(4-nitrophenyl)-1<i>H</i>-1,2,3-triazole (FNPT) as a pr...

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Bibliographic Details
Main Authors: Tomas Opsomer, Kaat Valkeneers, Ana Ratković, Wim Dehaen
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Organics
Subjects:
1,2,3-triazole
aldehyde
cycloaddition
enamine
Cornforth
rearrangement
Online Access:https://www.mdpi.com/2673-401X/2/4/24

Internet

https://www.mdpi.com/2673-401X/2/4/24

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