Polycomb contraction differentially regulates terminal human hematopoietic differentiation programs

Polycomb contraction differentially regulates terminal human hematopoietic differentiation programs

Abstract Background Lifelong production of the many types of mature blood cells from less differentiated progenitors is a hierarchically ordered process that spans multiple cell divisions. The nature and timing of the molecular events required to integrate the environmental signals, transcription fa...

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Bibliographic Details
Main Authors: A. Lorzadeh, C. Hammond, F. Wang, D. J. H. F. Knapp, J. CH. Wong, J. Y. A. Zhu, Q. Cao, A. Heravi-Moussavi, A. Carles, M. Wong, Z. Sharafian, J. Steif, M. Moksa, M. Bilenky, P. M. Lavoie, C. J. Eaves, M. Hirst
Format: Article
Language:English
Published: BMC 2022-05-01
Series:BMC Biology
Subjects:
Human hematopoietic cell differentiation
Epigenomics
H3K27me3
Hematopoietic progenitors
In vitro differentiation
Online Access:https://doi.org/10.1186/s12915-022-01315-1

Internet

https://doi.org/10.1186/s12915-022-01315-1

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