Multi-omics analyses reveal the specific changes in gut metagenome and serum metabolome of patients with polycystic ovary syndrome

Multi-omics analyses reveal the specific changes in gut metagenome and serum metabolome of patients with polycystic ovary syndrome

ObjectiveThe purpose of this study was to investigate the specific alterations in gut microbiome and serum metabolome and their interactions in patients with polycystic ovary syndrome (PCOS).MethodsThe stool samples from 32 PCOS patients and 18 healthy controls underwent the intestinal microbiome an...

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Bibliographic Details
Main Authors: Zhandong Yang, Huijiao Fu, Huihui Su, Xuzi Cai, Yan Wang, Yanjun Hong, Jing Hu, Zhiyong Xie, Xuefeng Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Microbiology
Subjects:
polycystic ovary syndrome
gut microbiota
shotgun metagenomics
serum metabolome
untargeted metabolomics
fecal microbiota transplantation
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.1017147/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.1017147/full

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