HBV X Protein Induces Degradation of UBXN7, a Novel Negative Regulator of NF-κB Signaling, to Promote HBV ReplicationSummary

HBV X Protein Induces Degradation of UBXN7, a Novel Negative Regulator of NF-κB Signaling, to Promote HBV ReplicationSummary

Chronic hepatitis B virus (HBV) infection is a leading cause of hepatocellular carcinoma. However, the function and mechanism of the effect of HBV on host protein ubiquitination remain largely unknown. We aimed at characterizing whether and how HBV promotes self-replication by affecting host protein...

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Bibliographic Details
Main Authors: Sen Yuan, Jiaqi Xu, Min Wang, Junsong Huang, Shuangshuang Ma, Yang Liu, Yujia Ke, Xianhuang Zeng, Kangwei Wu, Jingwen Wang, Xuezhang Tian, Dandan Zheng, Tanzeel Yousaf, Wajeeha Naz, Junwei Sun, Lang Chen, Deyin Guo, Mingxiong Guo, Guihong Sun
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
UBXN7
IKK-β
HBx
HBV Replication
Ubiquitination
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X22001953

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http://www.sciencedirect.com/science/article/pii/S2352345X22001953

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