Antigen presentation kinetics control T cell/dendritic cell interactions and follicular helper T cell generation in vivo
The production of high affinity, class switched antibodies produced by B cells hinges on the effective differentiation of T follicular helper (Tfh) cells. Here we define conditions specifically enhancing Tfh differentiation and providing protection in a model of influenza infection. Tfh responses we...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2015-08-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/06994 |