CXCL14 Maintains hESC Self-Renewal through Binding to IGF-1R and Activation of the IGF-1R Pathway

CXCL14 Maintains hESC Self-Renewal through Binding to IGF-1R and Activation of the IGF-1R Pathway

Human embryonic stem cells (hESCs) have important roles in regenerative medicine, but only a few studies have investigated the cytokines secreted by hESCs. We screened and identified chemokine (C-X-C motif) ligand 14 (CXCL14), which plays crucial roles in hESC renewal. CXCL14, a C-X-C motif chemokin...

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Bibliographic Details
Main Authors: Chih-Lun Cheng, Shang-Chih Yang, Chien-Ying Lai, Cheng-Kai Wang, Ching-Fang Chang, Chun-Yu Lin, Wei-Ju Chen, Po-Yu Lin, Han-Chung Wu, Nianhan Ma, Frank Leigh Lu, Jean Lu
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cells
Subjects:
CXCL14
BRAK
BMAC
Mip-2γ
human embryonic stem cell
self-renewal
Online Access:https://www.mdpi.com/2073-4409/9/7/1706

Internet

https://www.mdpi.com/2073-4409/9/7/1706

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