Factor H preserves alternative complement function during ARDS, linked to improved survival

Background Effective regulation of complement activation may be crucial to preserving complement function during acute respiratory distress syndrome (ARDS). Factor H is the primary negative regulator of the alternative pathway of complement. We hypothesised that preserved factor H levels are associa...

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Bibliographic Details
Main Authors: William Bain, Mohammadreza Tabary, Sara R. Moore, Xiaojing An, Georgios D. Kitsios, Bryan J. McVerry, Prabir Ray, Anuradha Ray, Rama K. Mallampalli, Viviana P. Ferreira, Janet S. Lee, S. Mehdi Nouraie
Format: Article
Language:English
Published: European Respiratory Society 2023-06-01
Series:ERJ Open Research
Online Access:http://openres.ersjournals.com/content/9/3/00702-2022.full