Mechanically transduced immunosorbent assay to measure protein-protein interactions

Mechanically transduced immunosorbent assay to measure protein-protein interactions

Measuring protein-protein interaction (PPI) affinities is fundamental to biochemistry. Yet, conventional methods rely upon the law of mass action and cannot measure many PPIs due to a scarcity of reagents and limitations in the measurable affinity ranges. Here, we present a novel technique that leve...

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Bibliographic Details
Main Authors: Christopher J Petell, Kathyrn Randene, Michael Pappas, Diego Sandoval, Brian D Strahl, Joseph S Harrison, Joshua P Steimel
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-09-01
Series:eLife
Subjects:
METRIS
protein-protein interactions
epigenetics
ubiquitin
UHRF1
DIDO1
Online Access:https://elifesciences.org/articles/67525

Internet

https://elifesciences.org/articles/67525

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