Synthesis of Hydantoin Androgen Receptor Antagonists and Study on Their Antagonistic Activity

Synthesis of Hydantoin Androgen Receptor Antagonists and Study on Their Antagonistic Activity

Hydroxymethylthiohydantoin, hydroxymethylthiohydantoin, and hydantoin, containing a pyridine group, were synthesized to study their androgen receptor antagonistic activities. Among them, compounds <b>6a</b>/<b>6c</b>/<b>7g</b>/<b>19a</b>/<b>19b&l...

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Bibliographic Details
Main Authors: Longjun Ma, Yan Zhou, Dehua Yang, Ming-Wei Wang, Wei Lu, Jiyu Jin
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Molecules
Subjects:
androgen receptor
antagonist
enzalutamide
hydantoin analogs
antiproliferative
Online Access:https://www.mdpi.com/1420-3049/27/18/5867

Internet

https://www.mdpi.com/1420-3049/27/18/5867

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