Metallo-Beta-Lactamase-like Encoding Genes in Candidate Phyla Radiation: Widespread and Highly Divergent Proteins with Potential Multifunctionality

Metallo-Beta-Lactamase-like Encoding Genes in Candidate Phyla Radiation: Widespread and Highly Divergent Proteins with Potential Multifunctionality

The Candidate Phyla Radiation (CPR) was found to harbor a vast repertoire of genes encoding for enzymes with potential antibiotic resistance activity. Among these, as many as 3349 genes were predicted in silico to contain a metallo-beta-lactamase-like (MBL-like) fold. These proteins were subject to...

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Bibliographic Details
Main Authors: Mohamad Maatouk, Vicky Merhej, Pierre Pontarotti, Ahmad Ibrahim, Jean-Marc Rolain, Fadi Bittar
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Microorganisms
Subjects:
Candidate Phyla Radiation
bacteria
metallo-beta-lactamase fold
massive analysis
functional diversity
sequence similarity network
Online Access:https://www.mdpi.com/2076-2607/11/8/1933

Internet

https://www.mdpi.com/2076-2607/11/8/1933

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