Systematic analysis of FKBP inducible degradation domain tagging strategies for the human malaria parasite Plasmodium falciparum.

Targeted regulation of protein levels is an important tool to gain insights into the role of proteins essential to cell function and development. In recent years, a method based on mutated forms of the human FKBP12 has been established and used to great effect in various cell types to explore protei...

Full description

Bibliographic Details
Main Authors: Mauro Ferreira de Azevedo, Paul R Gilson, Heloisa B Gabriel, Roseli F Simões, Fiona Angrisano, Jacob Baum, Brendan S Crabb, Gerhard Wunderlich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3397994?pdf=render