Influence of the Degree of Deacetylation of Chitosan and BMP-2 Concentration on Biocompatibility and Osteogenic Properties of BMP-2/PLA Granule-Loaded Chitosan/β-Glycerophosphate Hydrogels

Influence of the Degree of Deacetylation of Chitosan and BMP-2 Concentration on Biocompatibility and Osteogenic Properties of BMP-2/PLA Granule-Loaded Chitosan/β-Glycerophosphate Hydrogels

Compositions based on chitosan/β-glycerophosphate hydrogels with highly porous polylactide granules can be used to obtain moldable bone graft materials that have osteoinductive and osteoconductive properties. To eliminate the influence of such characteristics as chain length, degree of purification,...

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Bibliographic Details
Main Authors: Andrey Vyacheslavovich Vasilyev, Valeriya Sergeevna Kuznetsova, Tatyana Borisovna Bukharova, Timofei Evgenevich Grigoriev, Yuriy Dmitrievich Zagoskin, Irina Alekseevna Nedorubova, Igor Ivanovich Babichenko, Sergey Nicolaevich Chvalun, Dmitry Vadimovich Goldstein, Anatoliy Alekseevich Kulakov
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Molecules
Subjects:
chitosan
deacetylation degree
osteoplastic material
BMP-2
porous polylactide granules
osteoinduction
Online Access:https://www.mdpi.com/1420-3049/26/2/261

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https://www.mdpi.com/1420-3049/26/2/261

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