Genomic diversity contributes to the neuroinvasiveness of the Yellow fever French neurotropic vaccine

Abstract Mass vaccination with the live attenuated vaccine YF-17D is the current way to prevent infection with Yellow fever virus (YFV). However, 0.000012–0.00002% of vaccinated patients develop post-vaccination neurological syndrome (YEL-AND). Understanding the factors responsible for neuroinvasion...

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Bibliographic Details
Main Authors: Florian Bakoa, Christophe Préhaud, Guillaume Beauclair, Maxime Chazal, Nathalie Mantel, Monique Lafon, Nolwenn Jouvenet
Format: Article
Language:English
Published: Nature Portfolio 2021-04-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-021-00318-3