Integration of single-cell RNA sequencing and bulk RNA transcriptome sequencing reveals a heterogeneous immune landscape and pivotal cell subpopulations associated with colorectal cancer prognosis

Integration of single-cell RNA sequencing and bulk RNA transcriptome sequencing reveals a heterogeneous immune landscape and pivotal cell subpopulations associated with colorectal cancer prognosis

IntroductionColorectal cancer (CRC) is a highly heterogeneous cancer. The molecular and cellular characteristics differ between the colon and rectal cancer type due to the differences in their anatomical location and pathological properties. With the advent of single-cell sequencing, it has become p...

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Bibliographic Details
Main Authors: Qian Zhang, Yang Liu, Xinyu Wang, Cheng Zhang, Mingxiao Hou, Yunen Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Immunology
Subjects:
single cell
immune landscape
colorectal cancer
tumor-associated macrophages
Treg
plasma B cell
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1184167/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1184167/full

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